MO HealthNet making the following changes to the Preferred Drug Listing for Insulin Agents

12/20/2023

Effective January 11, 2024, in response to various changes in the current marketplace, MO HealthNet will make the following changes to the Preferred Drug Listing for Insulin Agents. For further information, please reference the Pharmacy Clinical Edits and Preferred Drug Lists webpage at Missouri Pharmacy Clinical Edits and Preferred Drug Lists | Missouri Department of Social Services (mo.gov).

Levemir® FlexPen®/FlexTouch®/Vial will be listed as a non-preferred agent based on Novo Nordisk’s decision to discontinue Levemir in the United States.
Participants compliant on non-preferred therapy will be allowed to continue therapy with the same non-preferred agent.

Preferred Agents	Non-Preferred Agents
Lantus® SoloStar®/Vial	Basaglar® KwikPen, Tempo™ Pen Insulin Degludec Pen/Vial Insulin Glargine Solostar U100 & 100 Unit/mL Vial Insulin Glargine-YFGN (gen Semglee®) Levemir® FlexPen®/FlexTouch®/Vial Rezvoglar™ Semglee® (YFGN) Toujeo® SoloStar®/Max SoloStar® Tresiba® FlexTouch®/Vial

Insulin Aspart FlexPen®/PenFill®/Vial (generic Novolog®) will be listed as a preferred agent.
Insulin Lispro Vial (generic Humalog®) will be listed as a preferred agent.
Humalog® Cartridge/Vial will be listed as a non-preferred agent.
NovoLog® FlexPen®/Vial will be listed as a non-preferred agent.
Participants compliant on Humalog® Cartridge therapy will be allowed to continue therapy with that agent.

Preferred Agents	Non-Preferred Agents
Insulin Aspart FlexPen®/ PenFill®/Vial Insulin Lispro Vial	Admelog® SoloStar® Pen/Vial Afrezza® Cartridge Apidra® SoloStar® Pen/Vial Fiasp® FlexTouch®/PenFill®/Vial Humalog® Cartridge/Vial Humalog® Jr KwikPen® Humalog® KwikPen®, Tempo™ Pen Insulin Lispro Jr KwikPen® Insulin Lispro KwikPen® Lyumjev® NovoLog® FlexPen®/PenFill®/Vial

Insulin Aspart Protamine and Insulin Aspart 70/30 FlexPen®/Vial (generic Novolog® Mix 70/30) will be listed as a preferred agent.
Insulin Lispro Mix 75/25 KwikPen® (generic Humalog® Mix 75/25™ KwikPen®) will be listed as a preferred agent.
Humalog® Mix 50/50™ KwikPen®/Vial will be listed as a non-preferred agent.
Humalog® Mix 75/25™ KwikPen®/Vial will be listed as a non-preferred agent.
NovoLog® Mix 70/30 FlexPen®/Vial will be listed as a non-preferred agent.
Participants compliant on Humalog® 50/50 products or Humalog® 75/25 vials will be allowed to continue therapy with those agents.

Preferred Agents	Non-Preferred Agents
Humulin® 70/30 Vial Insulin Aspart Protamine and Insulin Aspart 70/30 FlexPen®/Vial Insulin Lispro Mix 75/25 KwikPen®	Humalog® Mix 50/50™ KwikPen®/Vial Humalog® Mix 75/25™ KwikPen®/Vial Humulin® 70/30 KwikPen® Novolin® 70/30 FlexPen®/Vial NovoLog® Mix 70/30 FlexPen®/Vial

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